The goal of the Annual Meeting on Data and AI in Social Sciences (MDAISS) is to create a sustainable platform in which students, researchers, entrepreneurs, policymakers, and practitioners put into practice theories and applications of data science (artificial intelligence or AI, machine learning or ML, big data) and social sciences for the well-being of the African continent. MDAISS’s first edition will provide an opportunity for training and discussion and a pathway for the practical development of data-science-based projects to boost entrepreneurship skills and youth employment in sub-Saharan Africa.